TimeWarp vs. NOVOS Core
NOVOS tested its formula in a human trial.TimeWarp built the broader daily system.
NOVOS Core combines 12 ingredients in one daily powder sachet. The TimeWarp Longevity Protocol brings together 25 compounds across its daily protocol and monthly pulse, with advanced delivery formats, pre-portioned capsules and integrated longevity tracking.
The short version
NOVOS Core is a tested formula. TimeWarp goes broader.
NOVOS Core is the only formula in our comparison tested as a finished product. In the STAMINA trial, published in European Heart Journal Open in November 2026 and supported by NOVOS, 61 adults aged 40 and over were randomized to NOVOS Core or placebo for six months; 43 completed both visits. The Core group improved on blood vessel function, arterial stiffness and systolic blood pressure. These are vascular markers, not proof of longer life or reversed biological age. NOVOS also offers NMN as a separate add-on, NOVOS Boost, and a biological age test.
The TimeWarp Longevity Protocol is built as a complete daily system: 25 compounds to NOVOS Core's 12, including NMN with apigenin, dedicated telomere support from cycloastragenol, 500 mg urolithin A, spermidine, a four-part sulforaphane system with delayed-release delivery, and a monthly senolytic pulse. On our formulation scorecard it reaches full strength on 10 of 12 drivers to NOVOS Core's 3, all in capsules, with the TimeWarp app built in.
Head to head
Side by side, compound for compound.
| TimeWarp | NOVOS Core | |
|---|---|---|
| Product compared | TimeWarp Longevity Protocol | NOVOS Core |
| Drivers of aging covered | 12 of 12 | 6 of 12 |
| At full strength (TimeWarp rating) | 10 | 3 |
| Compounds | 25, across the daily protocol and monthly pulse | 12 |
| NAD+ support | NMN 350 mg with apigenin | Not in Core. NMN is available as a separate add-on, NOVOS Boost |
| Telomere support | Cycloastragenol, 10 mg | No dedicated telomere compound |
| Urolithin A, for cellular energy | 500 mg | Not included |
| Sulforaphane | Four-part system: glucoraphanin 70 mg, myrosinase, vitamin C, delayed-release capsule | Not included |
| Ca-AKG | 1,000 mg | 1,100 mg |
| Spermidine | 10 mg | Not included |
| Senolytic | Monthly pulse: liposomal fisetin 300 mg, isoquercetin 150 mg and bromelain 480 mg, 2 days a month | Fisetin 100 mg, daily |
| Methylated B vitamins, D3 and K2 | Included | Not included |
| Format | Capsules only | Powder sachet mixed into a drink |
The drivers of aging
How each formula covers the drivers of aging.
NOVOS describes Core as designed to target all 12 hallmarks of aging at once. Our scorecard applies a stricter, ingredient-level test: we mapped every compound in both formulas to the twelve drivers a supplement can target, at the dose printed on the label. On that test, TimeWarp reaches full strength on 10 of the 12 and NOVOS Core on 3, with 6 covered at moderate or above. Tap any driver to see the compounds behind each rating.
Genomic instabilityWhyStrongWeak
TimeWarpBeta-NMN 350 mg, 5-MTHF 500 mcg and methylcobalamin 200 mcg support DNA repair and methylation, with pterostilbene 50 mg and the sulforaphane complex for antioxidant defense.
NOVOS CoreVitamin C 100 mg and pterostilbene 50 mg offer antioxidant support. Rated Weak because Core has no NAD+ precursor (NOVOS sells NMN separately as Boost) or methylation support.
Telomere attritionWhyStrongVery weak
TimeWarpStandardized cycloastragenol 10 mg, one of the few compounds shown to activate telomerase, the enzyme that rebuilds telomeres. In a one-year randomized, placebo-controlled trial of an astragalus-derived telomerase activator, telomeres grew while the placebo group's shortened. Supported by vitamin D3 50 mcg, which slowed telomere loss in the 1,031-person VITAL trial.
NOVOS CoreLithium 1 mg has limited research on telomere length, mostly at prescription doses. No ingredient directly targets telomere maintenance.
Epigenetic alterationsWhyStrongStrong
TimeWarpCa-AKG 1,000 mg as a TET enzyme cofactor, the complete methylation cycle (5-MTHF, B12 and B6) and pterostilbene 50 mg.
NOVOS CoreCa-AKG 1,100 mg as a TET enzyme cofactor, with pterostilbene 50 mg.
Loss of proteostasisWhyStrongModerate
TimeWarpThe sulforaphane complex activates NRF2, alongside spermidine 10 mg and liposomal EGCG 80 mg.
NOVOS CoreGlycine 2 g and glucosamine 1 g support protein quality control. Rated Moderate because the formula has no NRF2 activator, the pathway behind the cell's main protein-protection response.
Deregulated nutrient sensingWhyStrongStrong
TimeWarpBeta-NMN 350 mg, dihydroberberine 100 mg through AMPK, Ca-AKG 1,000 mg and pterostilbene 50 mg.
NOVOS CoreCa-AKG 1,100 mg, glucosamine 1,000 mg and pterostilbene 50 mg act on nutrient-sensing pathways.
Mitochondrial dysfunctionWhyStrongModerate
TimeWarpBeta-NMN 350 mg, Ca-AKG 1,000 mg and magnesium bisglycinate 200 mg.
NOVOS CoreCa-AKG 1,100 mg and magnesium malate support energy metabolism. Rated Moderate because Core has no NAD+ precursor.
Cellular senescenceWhyStrongWeak
TimeWarpThe monthly pulse: liposomal fisetin 300 mg, isoquercetin 150 mg and bromelain 480 mg on each of two days, following the intermittent schedule used in senolytic research. Human evidence for senolytic supplements is still early.
NOVOS CoreFisetin 100 mg, taken daily. Rated Weak because it is a single senolytic compound at a low daily dose; senolytic research has mostly tested short, intermittent courses, often with a partner such as quercetin.
Stem cell exhaustionWhyModerateWeak
TimeWarpCa-AKG 1,000 mg and beta-NMN 350 mg support the energy metabolism stem cells rely on. Rated Moderate because human evidence for any supplement on stem cell function is still early.
NOVOS CoreCa-AKG 1,100 mg supports the energy metabolism stem cells rely on. Rated Weak because it is the only compound for this driver, where TimeWarp pairs Ca-AKG with NMN.
Altered intercellular communicationWhyStrongVery weak
TimeWarpVitamin D3 50 mcg, vitamin K2 MK-7 150 mcg, liposomal curcumin 150 mg and rhodiola 200 mg.
NOVOS CoreGinger extract and vitamin C have modest effects on inflammatory signaling, but the formula has no vitamin D or other immune-signaling compound at a meaningful dose.
Disabled macroautophagyWhyStrongStrong
TimeWarpSpermidine 10 mg, a polyamine studied for its role in autophagy.
NOVOS CoreGlucosamine 1,000 mg and Ca-AKG 1,100 mg, both studied for their effects on autophagy, with pterostilbene 50 mg.
Chronic inflammationWhyStrongModerate
TimeWarpLiposomal curcumin 150 mg through NF-κB, the sulforaphane complex through NRF2, apigenin 50 mg and liposomal EGCG 80 mg.
NOVOS CoreGinger root extract, glycine 2 g and fisetin 100 mg all have anti-inflammatory research. Rated Moderate because the human evidence at these doses is more limited than for compounds like curcumin, which carry a Strong rating.
DysbiosisWhyModerateVery weak
TimeWarpDihydroberberine 100 mg, from the berberine family studied for its effects on the gut microbiome, with liposomal EGCG, curcumin and the sulforaphane complex supporting a healthy gut environment. The TimeWarp app builds fiber and diet habits into your day. Rated Moderate because the formula has no probiotic.
NOVOS CoreGinger and glucosamine have early research on the gut microbiome, but neither is included for this driver, and the formula has no probiotic or prebiotic.
This comparison rates the 12 hallmarks in the 2023 framework, the molecular and cellular drivers a formula can target. A 2025 update in Cell proposed two more, extracellular matrix changes and psychosocial isolation, which are shaped largely by daily habits. The TimeWarp formula targets pathways linked to the first 12, and the TimeWarp app supports the habits associated with the newest two, like strength training and social connection. Together, the TimeWarp Longevity Protocol covers all 14.
“Full strength” is TimeWarp's own classification, not a clinical standard: a compound with an established mechanism for that driver, at a dose consistent with published human research, including clinical trials and human intake studies, in a form whose bioavailability supports that dose. Ratings measure formulation coverage, not proven clinical benefit. See the full scorecard method.
Senolytics
Hit and run, or every day?
Senolytics help clear senescent cells, the worn-out cells that build up with age. Senolytic research doses them in short bursts with weeks off in between, an approach known as hit and run, because cleared cells take weeks to build back up. A low daily dose takes a different approach.
TimeWarp
Hit and run
- Included
- Yes, a dedicated monthly Senolytic Pulse
- Schedule
- Two days a month, then weeks off
- What’s in it
- Liposomal fisetin 300 mg with isoquercetin 150 mg and bromelain 480 mg, in its own capsules
NOVOS Core
Every day
- Included
- Senolytic compound inside the daily powder
- Schedule
- Every day, at a low dose
- What’s in it
- Fisetin 100 mg, mixed into a powder
The daily routine
What your morning looks like.
Tear, take, done.
- Tear open your daily sachet. Everything is pre-sorted.
- Take six capsules with your first meal.
- Log it in the TimeWarp app and keep your streak going.
- Two days a month, add your senolytic reset.
One sachet, mixed into a drink.
- Empty one sachet into water or your favorite drink.
- Stir it and drink it, at any time of day.
- Repeat every day.
The real price
The real monthly cost of each.
As sold, NOVOS Core costs less. It also does not include three of the TimeWarp formula's most expensive compounds. Below, we price what it would take to add them as separate supplements.
About $8.63 a day. A hypothetical, partial regimen, not a product NOVOS sells. It still leaves out NMN, spermidine, the monthly senolytic pulse and other TimeWarp compounds, and adding these would change how it scores.
$249/mo
About $8.30 a day, with every compound, the monthly senolytic pulse and the TimeWarp app included.
Start Your ProtocolNOVOS prices from novoslabs.com, verified November 11, 2026. Add-on prices are retail, at the low end of our cost breakdown, for a 30-day supply at the TimeWarp doses: cycloastragenol 10 mg, urolithin A 500 mg, and a glucoraphanin supplement with myrosinase. NOVOS Core includes a daily senolytic, so no senolytic pulse is added, and NMN is not added either. TimeWarp price is the quarterly plan. See the full cost breakdown.
The daily ritual
Tear. Take. Done.
Your whole longevity routine in ten seconds. At home, at work, on a plane.
- 01
Tear
One daily sachet. Everything pre-sorted, nothing to measure.
- 02
Take
Six capsules with your first meal. Two days a month, add your senolytic reset.
- 03
Done
Log it in the TimeWarp app and watch your streak build.
You don’t settle. Neither does your formula.
25 compounds at clinical and research-level amounts, across the daily protocol and monthly pulse, for less than half the mid-range cost of buying them separately (about $530 a month, itemized in our cost breakdown).
What you’re investing in
Because this is not a bottle.
Protocol 01 is a fully engineered monthly system designed to make a serious longevity routine easier to follow, easier to trust, and harder to abandon. It consolidates 25 compounds, advanced delivery, and the TimeWarp app into a single routine built for adherence, clarity, and long-term use.
You are not paying for more capsules. You are paying for a better system.
Start Your Protocol$300
one-time purchase
30-day supply. Daily protocol + monthly senolytic pulse. Full TimeWarp app access.
Buy Once30 daily sachets · 2 monthly sachets · TimeWarp app
Regular price $900$747
every 3 months
$249/month · about $8.30/day
90-day supply shipped every quarter. Lock in the compounding advantage. Cancel anytime. The protocol is designed to reward consistency.
Start Your Protocol90 daily sachets · 6 monthly sachets · TimeWarp app · Priority support
Over 5,000 people joined the waitlist before launch.
Most approaches to longevity focus on single pathways. But aging doesn't work that way. It emerges from interactions across biological systems, where the hallmarks influence and reinforce each other.
30-Day Guarantee on your First Quarterly Subscription
Protocol 01 is built for serious daily use. Start on the Quarterly plan and give it 30 days. If it isn't for you, keep the box you started, send back the other two unopened and in their plastic wrap, and get your first payment back.
Start today. Build the routine. Compound it over years.
Questions
TimeWarp vs. NOVOS Core, answered.
How does TimeWarp compare with NOVOS Core?
NOVOS Core has a published, placebo-controlled trial of its finished formula, which showed improvements in vascular markers. TimeWarp's evidence is at the ingredient level, with doses based on clinical or research-level amounts. On our formulation scorecard, the TimeWarp Longevity Protocol covers all 12 drivers of aging a supplement can target, 10 at full strength, and NOVOS Core covers 6, 3 at full strength. TimeWarp has 25 compounds to NOVOS Core's 12, including NMN, cycloastragenol, urolithin A, spermidine, a four-part sulforaphane system and a monthly senolytic pulse. These ratings compare formulations, not clinical outcomes.
Does TimeWarp cover all 14 hallmarks of aging?
Yes. The formula targets pathways linked to the 12 molecular and cellular hallmarks in the 2023 framework, 10 of them at full strength on our scorecard. A 2025 update proposed two more, extracellular matrix changes and psychosocial isolation, which are shaped largely by daily habits. The TimeWarp app supports habits linked to them, such as strength training and social connection. We compare formulas on the 12 because those are the ones a capsule can target.
Is NOVOS Core cheaper than TimeWarp?
Yes, as sold. NOVOS Core is $98 a month on subscription, $79 a month on the annual plan, or $109 one-time. The TimeWarp Longevity Protocol is $249 a month on the quarterly plan, about $8.30 a day. NOVOS Core does not include cycloastragenol, urolithin A or a glucoraphanin supplement with myrosinase. Bought separately at retail, those three add about $161 a month, which would bring an illustrative, partial regimen to about $259. That regimen is not a NOVOS product and still leaves out NMN, spermidine and the monthly pulse.
What does TimeWarp include that NOVOS Core doesn't?
NMN with apigenin for NAD+ support, dedicated telomere support from cycloastragenol, 500 mg urolithin A, spermidine 10 mg, a four-part sulforaphane system with delayed-release delivery, dihydroberberine, liposomal curcumin and EGCG, and methylated B vitamins with D3 and K2. Plus a monthly senolytic pulse taken two days a month, and the TimeWarp app built in.
Is TimeWarp a powder like NOVOS Core?
No. Every compound is in capsules: six a day from one daily sachet, plus two days a month of the senolytic pulse. Capsules can carry bitter or strong-tasting compounds at full dose, with nothing to mix and nothing to taste.
Can I take TimeWarp and NOVOS Core together?
Several compounds overlap, including Ca-AKG, pterostilbene, fisetin, rhodiola and magnesium, so taking both would double some doses. The TimeWarp Longevity Protocol is built as a complete daily system on its own. If you take other supplements, check with your doctor first.
Is there a guarantee?
Yes. Your first quarterly order of the TimeWarp Longevity Protocol comes with a 30-day guarantee.
NOVOS is a trademark of its owner, used here only to identify the product compared. TimeWarp Labs is not affiliated with NOVOS Labs. This page compares NOVOS Core, not NOVOS's full range, which also includes NOVOS Boost. Details from the NOVOS Core label and product page at novoslabs.com, verified November 11, 2026. Scores and ratings are TimeWarp's own assessment of formulation coverage, not comparisons of clinical outcomes.
